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Table 6 Model input parameters calculated from field data

From: Insecticide resistance evolution with mixtures and sequences: a model-based explanation

Field data

Pyrethroid, Kdr [26]

rescaled pyrethroid, Kdr [26]

Carbamate, Ace1 [27]

Exposed survival RR

0.83

1

0.84

Exposed survival SR

0.72

0.87

0.56

Exposed survival SS

0.59

0.71

0.02

Unexposed survival RR

0.67

0.81

–

Unexposed survival SR

0.50

0.60

–

Unexposed survival SS

0.83

1

–

Calculated model inputs

 Effectiveness

0.41

0.29

0.98

 Resistance restoration

0.60

1

0.84

 Dominance of resistance

0.52

0.54

0.66

 Cost of resistance

–

0.19

–

 Dominance of cost

–

1a

–

  1. aFor the pyrethroid the unexposed survival of the SR (0.5) was less than that for the RR (0.67) This indicates underdominance which is biologically unlikely for unexposed genotypes so dominance was set to 1 so that SR and RR genotypes have the same fitness costs. The authors indicated that surprisingly high mortality in the control huts may have been due to rough handling [26] and this could contribute to the unexpected values here