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Table 5 Haplotypes frequencies estimations in the population and association with severe malaria (SM)

From: Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population

Haplotypes Frequencies Case vs. controls (Fisher exact test)
Global Case (SM) Controls (UM + CTR)
H1
 CCA 0.2 0.2 0.2 p = 0.19
H2
 GGT
OR (95% CI)
0.17 0.24 0.14 p = 0.03
4.1 (2.114.9)
H3
 GGA 0.08 0.12 0.07 p = 0.11
  1. Haplotypes analysis using Thesias program, and description of the association between cases SM (cases) vs. Control group (UM + CTR) using fisher exact test. Haplotype 2 was significantly associated with susceptibility to SM. SM Severe malaria, UM Uncomplicated malaria, CTR Control group. The significant p value of the haplotype H2 is in bold; OR 95% CI values were emphisized in italic format