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Table 1 Prevalence and multiplicity of infection (MOI) of msp-1 and msp-2 allelic types in Plasmodium falciparum isolates from Grande Comore Island in two different periods

From: Temporal changes in genetic diversity of msp-1, msp-2, and msp-3 in Plasmodium falciparum isolates from Grande Comore Island after introduction of ACT

Gene types Isolates collected in 2006–2007 period Isolates collected in 2013–2016 period
No. of samples (%) MOI No. of samples (%)a MOIb
msp-1
 K1 7 (6.3) 2.28 26 (23.6)** 1.70##
 MAD20 3 (2.7) 2.33 14 (12.7)** 1.79##
 RO33 16 (14.3) 2.50 38 (34.5)** 1.34##
 K1 + MAD20 7 (6.3) 2.29 0 (0)** 0##
 K1 + RO33 41 (36.7) 3.46 20 (18.2)** 1.70##
 MAD20 + RO33 35 (31.3) 3.43 12 (10.9)** 2.08##
 K1 + MAD20 + RO33 3 (2.7) 2.67 0 (0) 0##
 Total 112 (100) 3.11 110 (100) 1.63##
msp-2
 FC27 10 (9.2) 2.30 71 (62.8)** 1.20##
 3D7 31 (28.4) 2.90 10 (8.8)** 2.30#
 FC27 + 3D7 68 (62.4) 2.75 32 (28.3)** 1.41##
 Total 109 (100) 2.75 113 (100) 1.35##
  1. aStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test
  2. bStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (# P < 0.05; ## P < 0.01) using t test