Genetic diversity and natural selection of Plasmodium knowlesi merozoite surface protein 1 paralog gene in Malaysia

Table 1 Estimates of nucleotide diversity, natural selection, haplotype diversity and neutrality indices of pkmsp1p

Domain	No. samples	SNPs	No. haplotype	Diversity ± SD		dN-dS	Codon based z test	Taj D	Fu & Li’s D*	Fu & Li’s F*
Domain	No. samples	SNPs	No. haplotype	Haplotype	Nucleotide	dN-dS	Codon based z test	Taj D	Fu & Li’s D*	Fu & Li’s F*
Full-length	36	339	35	0.998 ± 0.007	0.00941 ± 0.0005	− 7.43	P < 0.000	− 1.4	− 2.11	− 2.22
83 kDa	36	138	35	0.998 ± 0.007	0.0105 ± 0.0007	− 4.85	P < 0.000	− 1.09	− 1.48	− 1.59
30 kDa	36	64	34	0.997 ± 0.007	0.0113 ± 0.0009	− 3.1	P < 0.002	− 1.15	− 1.83	− 1.89
38 kDa	36	72	32	0.992 ± 0.009	0.0066 ± 0.0006	− 2.56	P < 0.01	− 1.96	− 2.94	− 3.09
38 kDa	36	72	32	0.992 ± 0.009	0.0066 ± 0.0006	− 2.56	P < 0.01	P < 0.05	P < 0.02	P < 0.02
33 kDa	36	49	34	0.997 ± 0.007	0.0095 ± 0.0007	− 3.56	P < 0.000	− 1.28	− 1.82	− 1.94
19 kDa	40	16	18	0.885 ± 0.038	0.00661 ± 0.0007	− 2.214	P < 0.02	− 1.75	− 2.93	− 3.02
19 kDa	40	16	18	0.885 ± 0.038	0.00661 ± 0.0007	− 2.214	P < 0.02	− 1.75	P < 0.02	P < 0.02

ISSN: 1475-2875