Skip to main content

Table 2 Study population stratified by gravidity and malaria infection status

From: Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

  Group PM status n (%) Gestational age (weeks)a
Mean (SD)
p valueb
Enrollment Primigravid PM− 104 21.4 (7.1) 0.8
PM+ 67 (39.2%) 22.1 (4.7)  
Secundigravid PM− 92 20.3 (6.7) 0.2
PM+ 34 (27.0%) 22.1 (5.5)  
Multigravid PM− 302 21.1 (6.3) 0.7
PM+ 58 (16.1%) 21.6 (6.6)  
Gestational week 30–32 Primigravid PM− 122   
PM+ 14 (10.3%)   
Secundigravid PM− 90   
PM+ 4 (4.3%)   
Multigravid PM− 270   
PM+ 15 (5.3%)   
Delivery Primigravid PM− 144 37.6 (4.2) 0.03
PM+ 27 (15.8%) 36.6 (4.1)  
Secundigravid PM− 109 37.7 (5.0) 0.8
PM+ 16 (12.8%) 38.6 (1.3)  
Multigravid PM− 326 38.6 (4.0) 0.2
PM+ 34 (9.4%) 39.6 (1.3)  
Pregnancy outcomec Primigravid Pregnancy loss 18 (61.1% BS +)   
PTD 26 (65.4% BS +)   
LBW 33 (66.6% BS +)   
SGA 18 (44.4% BS +)   
Secundigravid Pregnancy loss 9 (33.3% BS +)   
PTD 14 (42.9% BS +)   
LBW 19 (52.6% BS +)   
SGA 11 (63.6% BS +)   
Multigravid Pregnancy loss 17 (23.5% BS +)   
PTD 8 (37.5% BS +)   
LBW 20 (20.0% BS +)   
SGA 22 (28.6% BS +)   
  1. Pregnancy loss includes miscarriages, stillbirths and early neonatal death
  2. PTD Preterm delivery, LBW low birthweight, SGA small for gestational age
  3. aGestational age at delivery includes viable singleton births
  4. bComparison of gestational age between PM− and PM+ within gravidity group by Mann–Whitney test
  5. cPercentage of women that were infected during pregnancy