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Table 1 Baseline characteristics

From: Low risk of recurrence following artesunate–Sulphadoxine–pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan

 

P. falciparum

P. vivax a

All

N = 231

Pf-noPQ

N = 112

Pf-PQ1

N = 119

p

All

N = 78

Pv-PQ14

N = 39

Pv-noPQ

N = 39

p

N (%) male

117 (50.6%)

53 (47.3%)

65 (53.7%)

0.329

40 (51.3%)

20 (51.3%)

20 (51.3%)

1.000

New Halfa (%)

191 (100.0)

92 (48.2)

99 (51.8)

0.833

22 (100.0)

12 (54.5)

10 (45.5)

0.615

Gezira Slanj (%)

40 (100.0)

20 (50.0)

20 (50.0)

56 (100.0)

27 (48.2)

29 (51.8)

Median age in years, (IQR)

19.0 (12.0–28.0)

18.5 (12.0–28.0)

19.0 (12.0–28.0)

0.310

17.0 (10.0–27.0)

16.0 (10.0–23.0)

19.0 (9.0–30.0)

0.272

0–5 years, N (%)

18 (7.8%)

8 (44.4%)

10 (55.5%)

0.824

4 (5.1%)

3 (75.0%)

1 (25%)

0.615

 > 5 years, N (%)

213 (92.2%)

104 (48.8%)

109 (51.2%)

74 (94.1%)

36 (48.6%)

38 (51.4%)

Body Temp. mean °C (95% CI)

38.8 (38.7–38.8)

38.8 (38.7–38.9)

38.8 (38.8–38.9)

0.499

38.6 (38.4–38.7)

38.5 (38.4–38.7)

38.5 (38.4–38.7)

0.415

Median Hb in g/dl (IQR)

11.7 (10.8–12.8)

11.7 (10.7–12.8)

11.8 (10.9–12.8)

0.535

11.0 (10.4–13.0)

12.0 (10.9–13.0)

11.0 (10.0–12.3)

0.113

Anaemia (< 10 g/dl), N (%)

13 (5.6%)

8 (7.1%)

5 (4.2%)

0.332

8 (10.3%)

4 (10.3%)

4 (10.3%)

1.000

Weight, mean kg (95% CI)

57.4 (54.0–60.7)

56.7 (51.8–61.6)

58.0 (53.2–62.7)

0.357

47.2 (42.4–52.1)

44.3 (38.3–50.3)

50.1 (42.3–58.0)

0.119

Parasitaemia (µl−1), geometric mean (95% CI)

7840 (7443–8259)

7779 (7226–8375)

7898 (7333–8508)

0.321

6939 (6383–7544)

6933 (6164–7797)

6947 6135–7865)

0.956

Gametocytaemia (µl−1), geometric mean (95% CI)

0

0

0

1.000

252 (224–284)

245 (203–296)

259 (222–303)

0.449

Gametocytaemia, N (%)s

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000

78 (100.0%)

39 (100.0%)

39 (100.0%)

1.000

Mean G6PD activity (U/gHb) (95% CI)

9.95 (9.52–10.38)

10.06 (9.37–10.74)

9.85 (9.30–10.39)

0.316

9.57 (8.27–10.88)

9.79 (7.85–11.73)

9.40 (7.35–11.44)

0.381

  1. aIncludes one patient with P. falciparum/P. vivax mixed infection