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Table 5 Overview of main adverse events

From: Low risk of recurrence following artesunate–Sulphadoxine–pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan

Type of AE

Total

P. falciparum

P. vivax

Pf-noPQ

Pf-PQ1

p

Pv-noPQ

Pv-PQ14

p

Poor appetite, n (%)

222 (40.3)

93 (47.2)

75 (35.7)

0.012

30 (41.1)

24 (33.8)

0.366

Nausea, n (%)

145 (25.6)

58 (29.4)

60 (28.6)

0.533

13 (17.8)

14 (19.7)

0.769

Abdominal pain, n (%)

114 (20.7)

29 (14.7)

51 (24.3)

< 0.001

21 (28.8)

13 (18.3)

0.140

Vomiting, n (%)

37 (6.7)

15 (7.6)

13 (6.2)

0.536

5 (6.8)

4 (5.6)

0.518

Rash, n (%)

1 (0.2)

0 (0.0)

1 (0.5)

0.521

0 (0.0)

0 (0.0)

1.000

Other, n (%)

36 (6.5)

2 (1.0)

14 (6.7)

0.004

4 (5.5)

16 (22.5)

0.004

Total, n (%)

551

197

210

 

73

71

 
  1. Significant values are in italics (p < 0.05)