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Table 3 Theoretical (Zadd) and experimental (Zexp) ED50 ± SEM values of xylopic acid and cryptolepine co-administration in the anti-malarial test

From: Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei

ED50s (XA/CYP: 1:1)

Anti-malarial activity

Zadd (mg kg−1)

12.75 ± 0.33

Zexp (mg kg−1)

2.60 ± 0.41

Interaction index

0.2041