Table 4 Efficacy of first-line anti-malarials in three therapeutic efficacy monitoring sites in Angola, 2017
Efficacy (95% confidence intervals) | ||||||
|---|---|---|---|---|---|---|
Benguela | Zaire | Lunda Sul | ||||
DPb | ASAQa | ALa | ASAQa | ALa | DPb | |
Uncorrected | ||||||
Per-protocol day 28 | 100 (95–100) | 99 (94–100) | 92.8 (85–97) | 82.2 (72–89) | 90.1 (82–95) | 100 (95–100) |
Per-protocol day 42 | 94.6 (87–98) | – | – | – | – | 100 (95–100) |
Kaplan–Meier estimate day 28 | 100 (100–100) | 98.9 (97–100) | 92.7 (88–98) | 82.1 (75–90) | 90.1 (84–96) | 100 (100–100) |
Kaplan–Meier estimate day 42 | 94.6 (90–99) | – | – | – | – | 100 (100–100) |
PCR-corrected | ||||||
Per-protocol day 28 | 100 (97–100) | 100 (97–100) | 95.5 (89–98) | 93 (85–97) | 96.4 (90–99) | 100 (96–100) |
Per-protocol day 42 | 100 (96–100) | – | – | – | – | 100 (96–100) |
Kaplan–Meier estimate day 28 | 100 | 100 (97–100) | 95.5 (91–100) | 93.3 (88–99) | 96.5 (93–100) | 100 |
Kaplan–Meier estimate day 42 | 100 (96–100) | – | – | – | – | 100 |