Fig. 3
Network representation of compound combination synergies. Red thick edges represent high synergy and blue thin edges represent additivity. The level of thickness or redness is inversely related to gamma (calculated based on experiments) in average for the tree P. falciparum strains used in this study. Tacrolimus-hydroxyzine, raloxifene-thioridazine, represent highest synergistic compound pairs followed by ingenol-tacrolimus, tacrolimus-fulvestrant, tacrolimus-apicidin and raloxifene-megestrol pairs. Tacrolimus is synergistic with highest number of compounds (three)