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Table 3 Survival and fecundity of Anopheles mosquitoes at 6 days after feeding on ivermectin treated versus untreated mice

From: Differential susceptibilities of Anopheles albimanus and Anopheles stephensi mosquitoes to ivermectin

Species Treatment 1 day after mouse injections 3 days after mouse injections
Percent surviving (n) Eggs per female (± SD) Percent surviving (n) Eggs per female (± SD)
An. stephensi Ivermectin 15% (52) 2 = 76.5
p < 0.001
0.9 ± 1.6 T = 8.2
df = 13
p < 0.001
62% (66) 2 = 15.7
p < 0.001
30.8 ± 8.7 T = 1.0
df = 4
p = 0.373
Control 100% (56) 46.1 ± 25.9 96% (48) 44.7 ± 18.8
An. albimanus Ivermectin 56% (56) 2 = 11.3
p < 0.001
4.7 ± 8.1 T = 1.5
df = 17
p = 0.143
95% (57) 2 = 0.9
p = 0.332
25.2 ± 7.2 T = 0.2
df = 4
p = 0.864
Control 89% (52) 12.8 ± 13.2 85% (48) 24.8 ± 10.0
  1. Mice received subcutaneous injections of either ivermectin (600 mg/kg BW) or saline (control group). Three mice were used for each treatment. Cohorts of age-matched mosquitoes (n = sample size) were blood-fed 1 day after injections and 3 days after injections