Table 1 Comparative inhibitory activities of Proveblue and primaquine on Plasmodium yoelii, Plasmodium falciparum and Plasmodium cynomolgi
From: Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium
Drugs | Methylene blue | Primaquine | ||||
|---|---|---|---|---|---|---|
Parasites | IC50 (µM) | TI | Size reduction at 11 µM (%) | IC50 (µM) | TI | Size reduction at 11 µM (%) |
P. yoelii (MH) | > 100 | 1 | 10 | 0.64 ± 0.1a | 110a | ND |
P. falciparum (HH) | > 100 | 1 | 10 | 0.6 ± 0.06 | 66.5 | 100 |
P. cynomolgi (SH) | > 100 | 1 | 10 | 2.72 ± 0.34 | 14.22 | 70 |