From: Anti-plasmodial effect of plant extracts from Picrolemma huberi and Picramnia latifolia
Code | Description | Activity | Cytotoxicity | ||
---|---|---|---|---|---|
IC50 FCR3 ± SD | IC50 3D7 ± SD | CC50 ± SD | SI | ||
P. latifolia | Bark/leaves. Extraction by percolation with ethanol | 7.6 ± 6.3 | 7.0 ± 0.83 | 146.6 ± 19.6 | 19.4 |
Bark/petiole. Extraction by percolation with ethanol | 1.3 ± 0.09 | 1.21 ± 0.19 | 3.5 ± 0.48 | 2.9 | |
P. huberi | Leaves/petiole/rachis. Extraction with hexane | 39.3 ± 9.3 | 156.9 ± 12.7 | 142.5 ± 31.7 | 1.2 |
Leaves. Extraction with hexane | 19.2 ± 0.2 | 51.8 ± 4.8 | 143.7 ± 36.0 | 4 | |
Petiole/rachis. Extraction with hexane | 16.5 ± 0.01 | 19.0 ± 2.5 | 53.7 ± 6.7 | 3 | |
Petiole/rachis. Degreasing with hexane; extraction with ethanol/water (90:10). | 0.2 ± 0.04 | 0.33 ± 0.08 | 5.8 ± 0.8 | 21.9 | |
Cortex. Extraction with hexane. | 14.4 ± 0.04 | 17.7 ± 2.3 | 21.8 ± 0.3 | 1.4 | |
Cortex. Extraction with ethanol/water (90:10) | 0.05 ± 0.0 | 0.09 ± 0.005 | 3.6 ± 0.3 | 51.4 | |
Cortex. Degreasing with hexane; extraction with ethanol/water (90:10). | 0.04 ± 0.01 | 0.08 ± 0.03 | 0.38 ± 0.0 | 6.3 | |
P. huberi AMALFI | Cortex. Extraction with ethanol/water (90:10) | 0.18 ± 0.02 | – | – | – |
CQ | – | 0.064 ± 0.01 | 0.0057 ± 0.0 | 73.4 ± 11.4 | – |
FCCP | – | – | – | 0.36 ± 0.04 | – |