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Table 2 Malariometric indices of clinical and asymptomatic infections during the first year of life

From: Malaria incidence and prevalence during the first year of life in Nanoro, Burkina Faso: a birth-cohort study

 

Age groups

Total

0–3 months

3–6 months

6–9 months

9–12 months

Longitudinal survey (N = 734)

 Clinical episodes by qPCR [number (% out of total cases)]

50 (7)

122 (17)

231 (32.2)

314 (43.8)

717 (100)

 Total time at risk (person-months)

2197.07

2124.91

2056.62

1956.58

8335.18

 Incidence (per child-year)

0.27

0.69

1.35

1.92

1.03

 Parasite density by qPCR [median (IQR)]

1294 (116.5–6726)

2848 (79.1–15,356)

9044 (642–28,554)

24,823 (3607–57,492)

10,826.5 (876–38,021)

 Sub-microscopic infections [number (% out of cases per age group)]

12 (24)

29 (23.8)

39 (16.9)

34 (10.8)

114 (15.9)

 

Surveys timepoints

Total

3 months

6 months

9 months

12 months

Cross-sectional surveys

 Total participants per survey

678

631

587

638

2534a

 Asymptomatic infections by qPCR [number (%)]

120 (17.7)

127 (20.1)

108 (18.4)

200 (31.3)

555 (21.9)b

 Parasite density by qPCR [median (IQR)]

148 (4.2–1754)

24.9 (1–954.7)

454.9 (3.1–4524)

1288 (2.6–13,998)

347.8 (1.94–3534)

 Sub-microscopic infections [number (% out of cases per survey)]

58 (48.3)

69 (54.3)

49 (45.4)

79 (39.5)

255 (45.9)

  1. IQR interquartile range
  2. a Total samples screened for asymptomatic infections
  3. b Proportion of qPCR-positive samples out of total screened over the four cross-sectional surveys