Fig. 5

Late-acting lethality suppresses the effects of over-compensatory larval density dependence. a Cost per case averted (excluding initial capital investment in construction) for optimized release strategies of early-acting and late-acting SIT, for the parameters given in Table 1, as the strength of the larval density dependence \(\beta\) is increased. The density dependence runs from contest for \(\beta < 1\) to scramble for \(\beta > 1\). The number of cases averted is approximated by ([mean no. with no control − mean no. with control]/average duration of disease) \(\times\) no. of days). The change in the optimal release strategy is shown for b early SIT, and c late SIT for three specific values of \(\beta\). Artemisinin treatment is not used