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Fig. 8 | Malaria Journal

Fig. 8

From: Optimal control of malaria: combining vector interventions and drug therapies

Fig. 8

Migration can harm concentrated control efforts; distributed vector control with combined drug treatment is optimal. The proportion of hosts infected in each of three identical populations with SIT release ratios \(u_1\), \(u_2\) and \(u_3\), where migration is \(10\%\) between nodes except in a where there is no migration. a \(u_1=3\), \(u_2 = u_3 = w_i = 0\); b \(u_1=3\), \(u_2 = u_3 = w_i = 0\) (concentrated control); c \(u_1 = u_2 = u_3 = 1\). \(w_i = 0\) (distributed control); d \(u_i(t) = u_i^*(t)\), \(w_i = 0\) (optimal vector control); e \(u_i(t) = u^*(t)\), \(w_i(t) = w_i^*(t)\) (optimal combined drug treatment and vector control). f Cost breakdowns for the five scenarios plotted above. All parameters as in Table 1. Late-acting lethality is used

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