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Table 1 Clinical characteristics of Ret + CM and UM cases

From: Convalescent Plasmodium falciparum-specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure

Patient characteristic Ret + CM (n = 25) UM (n = 23) P-value*
Age (yr), median [IQR] 3.5 [3, 4] 4 [2, 7] 0.29
Male, n (%) 15 (60.0) 17 (73.9) 0.31
Parasite smear score, median [IQR] 2 [2, 4] 4 [3, 4] 0.01
Pfhrp2 (ng/ml), median [IQR] 2580 [566, 10, 506] 216 [57, 484] <0.001
Cell free Pf DNA (genomes per μl), median [IQR] 904 [414, 1703] 60 [5, 471] <0.001
Hgb (g/dL), median [IQR] 7.4 [6.4, 9.1] 9.6 [7.7, 11.5] 0.01
Platelets (103/μl), median [IQR] 66 [49, 88] 126 [64, 153] 0.03
Total WBC (103/μl), median [IQR] 8.8 [6.5, 11.9] 7.8 [6.0, 9.4] 0.20
Var targets amplifieda (of n = 48), median [IQR] 21 [17, 24] 11 [7, 17] <0.001
ICAM-1 motif amplifiedb, n (%) 10 (52.6%) 5 (21.7%) 0.04
Mortality, n (%) 0 (0) 0 (0) 1.00
  1. IQR, interquartile range; * P-values correspond to Wilcoxon rank-sum or Chi squared test
  2. aN = X targets total, amplified using primers from Lavstsen et al. [19], Mkumbaye et al. [44]
  3. bMotif amplified using primers from Lennartz et al. [32]; Ret + CM n = 19