Table 1 Summary of admission characteristics and outcomes of neonatal and congenital malaria
From: Neonatal and congenital malaria: a case series in malaria endemic eastern Uganda
Variable | Congenital malaria | Neonatal malaria | ||
|---|---|---|---|---|
Case 1 | Case 2 | Case 3 | Case 4 | |
Mother | ||||
Age (years) | 28 | 24 | 24 | 26 |
HIV status | Negative | Positive | Negative | Negative |
Parity | 2 + 1 | 3 + 0 | 1 + 0 | 1 + 0 |
Fever within 14 days of delivery | Yes | Yes | No | No |
Neonate | ||||
Age (days) | 2 | 1 | 14 | 16 |
Sex | M | F | M | F |
Birth weight (kg) | 2.7 | 1.7 | 3.5 | 2.8 |
Admission weight (kg) | 2.4 | 1.7 | 3.9 | 2.5 |
Symptoms | ||||
Fever | Yes | No | Yes | Yes |
Duration of fever (days) | 1 | 0 | 3 | 2 |
Fast breathing | Yes | No | No | Yes |
Breastfeeding | No | No | Yes | Yes |
Poor feeding | Yes | Yes | No | No |
Signs | ||||
Temperature (°C) | 40.1 | 34.8 | 36.1 | 39.1 |
Jaundice | Yes | No | No | No |
Pallor | Yes | No | No | No |
Respiratory rate (breath/m) | 104 | Not taken | Not taken | 72 |
Heart rate (BPM) | 225 | 108 | 166 | 113 |
SP02 (%) | 96 | 79 | 96 | 68 |
Hepatomegaly | No | No | No | No |
Splenomegaly | No | No | No | No |
Tachycardia | Yes | No | Yes | No |
Laboratory | ||||
CSF | ||||
Proteins (g/L) | 0.3 | No | No | < 0.1 |
Sugar (mmol/L) | 8.12 | No | No | 10.08 |
WBC | 75 × 106/L | No | No | < 5 × 106/L |
Malaria | ||||
Blood slide | Positive | Positive | Positive | Positive |
Treatment | ||||
Antibioticsa | Cefotaxime/Genta | Amp/Genta | Amp/Genta | Amp/Genta |
Anti-malarial | Artesunate | Artesunate | Artesunate | Artesunate |
Blood transfusion | No | No | No | No |
Oxygen | No | Yes | No | Yes |
Outcome | ||||
At discharge | Alive | Alive | Alive | Alive |