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Table 2 The percentage of resistant phenotypes of P. falciparum isolated from along the Thai–Cambodia border collected before 2009 and from 2009 to2016

From: Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project

Drug Total% (n) Before 2009% (n) 2009–2016% (n) p value
CQ 99.0 (100/101) 98.0 (49/50) 100 (51/51) 0.500
QN 0 (0/101) 0 (0/50) 0 (0/51)
MQ 39.6 (40/101) 22.0 (11/50) 56.9 (29/51) < 0.001
ARS 0 (0/101) 0 (0/50) 0 (0/51)
DHA 0 (0/95) 0 (0/44) 0 (0/51)
ATQ 0 (0/50) 0 (0/50)
  1. Significant differences of resistant phenotype between parasites collected before 2009 and from 2009 to 2016 determined using Fisher’s Exact test
  2. CQ resistance was defined as IC50 ≥ 25 nM, QN resistance was defined as IC50 > 800 nM, MQ resistance was defined as IC50 > 30 nM, ARS resistance was defined as IC50 > 10.5 nM, DHA resistance was defined as IC50 > 10.5 nM and ATQ resistance was defined as IC50 > 1900 nM