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Table 2 Odds ratios of Vgsc-1014 mutations and their association with study arm in 2010 and 2011

From: Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children

Kdr mutation status 2010 2011
LLIN only arm IRS-LLIN arm OR (95% CI) (adjusted for clustering) p value LLIN only arm IRS-LLIN arm OR (95% CI) (adjusted for clustering) p value
n (%) n (%) n (%) n (%)
Wild type 1761 (70.3%) 1015 (58.5%)    461 (53.9%) 250 (39.6%)   
Any Vgsc-1014 mutation 695 (27.7%) 693 (39.9%) 1.54 (1.07–2.22) 0.02 370 (43.2%) 344 (54.4%) 2.26 (1.24–4.11) 0.01
Heterozygous Vgsc-1014F 70 (2.8%) 103 (5.9%) 2.17 (1.28–3.68) 0.004 34 (4.0%) 31 (4.9%) 1.32 (0.75–2.33) 0.34
Homozygous Vgsc-1014F 167 (6.7%) 290 (16.7%) 2.24 (1.12–4.49) 0.02 169 (19.7%) 196 (31.0%) 2.52 (1.20–5.29) 0.01
Heterozygous Vgsc-1014S 412 (16.4%) 262 (15.1%) 0.86 (0.67–1.11) 0.26 149 (17.4%) 95 (15.0%) 0.71 (0.41–1.23) 0.22
Homozygous Vgsc-1014S 46 (1.8%) 38 (2.2%) 1.09 (0.60–1.99) 0.78 18 (2.1%) 22 (3.5%) 1.34 (0.53–3.36) 0.54
N 2506 1736    856 632