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Table 4 Association between explanatory variables and odds ratio of P. falciparum infection in children

From: Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children

Variable

2010 (end of transmission season)

2011 (end of transmission season)

P. falciparum infection at end of season

n/N (%)

Univariable analysis

Multivariable analysis

P. falciparum infection at end of season

n/N (%)

Univariable analysis

Multivariable analysis

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

Gender

 Male

99/796 (12.4%)

1

–

1

–

173/836 (20.7%)

1

–

1

–

 Female

123/747 (16.5%)

1.45 (1.08–1.96)

0.01

1.47 (1.08–1.98)

0.01

123/728 (16.9%)

0.74 (0.57–0.97)

0.03

0.73 (0.56–0.96)

0.02

Age of child (yrs)

–

1.06 (1.02–1.10)

0.007

1.06 (1.02–1.10)

0.007

–

1.13 (1.08–1.17)

< 0.001

1.12 (1.08–1.17)

< 0.001

Child slept under an LLIN the previous night

 No

20/142 (14.1%)

1

   

26/83 (31.3%)

1

–

  

 Yes

202/1400 (14.4%)

1.10 (0.64–1.87)

0.74

  

268/1479 (18.1%)

0.44 (0.26–0.74)

0.002

0.49 (0.28–0.83)

0.009

Study arm

          

 LLIN only

87/763 (11.4%)

1

–

  

153/823 (18.6%)

1

–

1

–

 LLIN and IRS

135/780 (17.3%)

1.51 (0.83–2.76)

0.18

  

143/741 (19.3%)

1.20 (0.69–2.09)

0.53

  

Bank of River Gambia

 North

118/812 (14.5%)

1

–

  

110/760 (14.5%)

1

–

  

 South

104/731 (14.2%)

1.05 (0.57–1.96)

0.87

  

186/804 (23.1%)

1.77 (1.05–2.97)

0.03

  

House construction

 Open eaves

124/848 (14.6%)

1

–

  

183/872 (21.0%)

1

–

  

 Closed eaves

79/609 (13.0%)

0.91 (0.63–1.30)

0.59

  

113/692 (16.3%)

0.81 (0.60–1.09)

0.16

  

Cluster level prevalence of [values in square brackets refer to OR for a 10% increase]

 Any Vgsc-1014 mutation

–

1.02 (1.00–1.04)

[1.20 (0.96-1.51)]

0.10

  

–

1.01 (1.00–1.02)

[1.10 (0.97–1.25)]

0.13

  

 Homozygous Vgsc-1014F

–

1.02 (1.00–1.05)

[1.25 (0.99-1.58)]

0.07

a

 

–

1.01 (1.00–1.02)

[1.13 (1.01–1.27)]

0.04

a

 

 An. gambiae s.s.

–

1.02 (1.00–1.04)

[1.27 (1.03–1.55)]

0.02

a

 

–

1.01 (1.00–1.02)

[1.12 (1.01–1.25)]

0.03

a

 
  1. a Variables colinear