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Table 4 Association between explanatory variables and odds ratio of P. falciparum infection in children

From: Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children

Variable 2010 (end of transmission season) 2011 (end of transmission season)
P. falciparum infection at end of season
n/N (%)
Univariable analysis Multivariable analysis P. falciparum infection at end of season
n/N (%)
Univariable analysis Multivariable analysis
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Gender
 Male 99/796 (12.4%) 1 1 173/836 (20.7%) 1 1
 Female 123/747 (16.5%) 1.45 (1.08–1.96) 0.01 1.47 (1.08–1.98) 0.01 123/728 (16.9%) 0.74 (0.57–0.97) 0.03 0.73 (0.56–0.96) 0.02
Age of child (yrs) 1.06 (1.02–1.10) 0.007 1.06 (1.02–1.10) 0.007 1.13 (1.08–1.17) < 0.001 1.12 (1.08–1.17) < 0.001
Child slept under an LLIN the previous night
 No 20/142 (14.1%) 1     26/83 (31.3%) 1   
 Yes 202/1400 (14.4%) 1.10 (0.64–1.87) 0.74    268/1479 (18.1%) 0.44 (0.26–0.74) 0.002 0.49 (0.28–0.83) 0.009
Study arm           
 LLIN only 87/763 (11.4%) 1    153/823 (18.6%) 1 1
 LLIN and IRS 135/780 (17.3%) 1.51 (0.83–2.76) 0.18    143/741 (19.3%) 1.20 (0.69–2.09) 0.53   
Bank of River Gambia
 North 118/812 (14.5%) 1    110/760 (14.5%) 1   
 South 104/731 (14.2%) 1.05 (0.57–1.96) 0.87    186/804 (23.1%) 1.77 (1.05–2.97) 0.03   
House construction
 Open eaves 124/848 (14.6%) 1    183/872 (21.0%) 1   
 Closed eaves 79/609 (13.0%) 0.91 (0.63–1.30) 0.59    113/692 (16.3%) 0.81 (0.60–1.09) 0.16   
Cluster level prevalence of [values in square brackets refer to OR for a 10% increase]
 Any Vgsc-1014 mutation 1.02 (1.00–1.04)
[1.20 (0.96-1.51)]
0.10    1.01 (1.00–1.02)
[1.10 (0.97–1.25)]
0.13   
 Homozygous Vgsc-1014F 1.02 (1.00–1.05)
[1.25 (0.99-1.58)]
0.07 a   1.01 (1.00–1.02)
[1.13 (1.01–1.27)]
0.04 a  
 An. gambiae s.s. 1.02 (1.00–1.04)
[1.27 (1.03–1.55)]
0.02 a   1.01 (1.00–1.02)
[1.12 (1.01–1.25)]
0.03 a  
  1. a Variables colinear