Table 3 Univariate analysis: Comparison of continuous clinical and EEG variables by outcome (mortality) (mean ± SD)
From: Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes
Country | Clinical or EEG variable | Alive (N = 101) | Died (N = 21) | p value |
|---|---|---|---|---|
Uganda | Age (years) | 3.8 ± 1.9 | 3.6 ± 2.1 | 0.77 |
Glucose (mg/dL) | 6.8 ± 3.3 | 5.6 ± 3.6 | 0.2622 | |
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] | 30,315.4 (21.9) | 53,669.7 (6.5) | 0.3463 | |
Lactate (mmol/L) | 4.9 ± 3.9 | 6.7 ± 4.1 | 0.0467 | |
Average voltage (µV) | 68.9 ± 31.9 | 50.5 ± 27.4 | 0.018 | |
Maximum voltage (µV) | 206.3 ± 71.0 | 158.0 ± 71.9 | 0.007 | |
Dominant frequency (Hz) | 2.0 ± 0.7 | 1.6 ± 0.9 | 0.02 |
Country | Clinical or EEG variable | Alive (N = 137) | Died (N = 22) | p value |
|---|---|---|---|---|
Malawi | Age (years) | 4.3 ± 2.3 | 4.1 ± 2.2 | 0.70 |
Glucose (mg/dL) | 7.1 ± 3.6 | 7.4 ± 4.1 | 0.8675 | |
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] | 31,053.5 (25.4) | 50,153.1 (13.6) | 0.4189 | |
Lactate (mmol/L) | 7.2 ± 4.1 | 8.6 ± 3.8 | 0.0827 | |
Average voltage (µV) | 112.2 ± 54.3 | 89.3 ± 58.2 | 0.08 | |
Maximum voltage (µV) | 213.8 ± 88.4 | 184.3 ± 88.2 | 0.17 | |
Dominant frequency (Hz) | 2.4 ± 1.1 | 1.9 ± 0.9 | 0.05 |
Country | Clinical or EEG variable | Alive (N = 238) | Died (N = 43) | p value |
|---|---|---|---|---|
Uganda + Malawi | Age (years) | 4.0 ± 2.1 | 3.8 ± 2.1 | 0.3459 |
Glucose (mg/dL) | 7.0 ± 3.5 | 6.5 ± 4.0 | 0.5049 | |
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] | 30,731.7 (23.5) | 51,793.8 (9.0) | 0.2168 | |
Lactate (mmol/L) | 6.2 ± 4.2 | 7.7 ± 4.0 | 0.0170 | |
Average voltage (µV) | 93.8 ± 50.8 | 69.9 ± 49.0 | 0.0032 | |
Maximum voltage (µV) | 210.6 ± 81.4 | 171.1 ± 80.6 | 0.0089 | |
Dominant frequency (Hz) | 2.2 ± 1.0 | 1.8 ± 0.9 | 0.0030 |