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Table 5 Univariate analysis: comparison of continuous clinical and EEG variables by outcome (neurological morbidity in survivors) (mean ± SD)

From: Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes

Country Clinical or EEG variable Alive and normal (N = 56) Alive with sequelae (N = 44) p value
Uganda Age (years) 3.8 ± 1.7 3.8 ± 2.2 0.5312
Glucose (mg/dL) 7.2 ± 3.3 6.4 ± 3.4 0.1376
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] 31,931.6 (23.3) 31,434.9 (18.7) 0.9755
Lactate (mmol/L) 4.6 ± 3.7 5.3 ± 4.2 0.4449
Average voltage (µV) 74.0 ± 32.1 63.6 ± 30.8 0.0723
Maximum voltage (µV) 213.8 ± 71.2 199.1 ± 70.3 0.3809
Dominant frequency (Hz) 2.0 ± 0.7 2.0 ± 0.6 0.9210
Country Clinical or EEG variable Alive and normal (N = 121) Alive with sequelae (N = 16) p value
Malawi Age (years) 4.3 ± 2.3 3.5 ± 1.9  
Glucose (mg/dL) 6.9 ± 2.9 8.3 ± 7.0 0.6468
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] 28,148.2 (27.4) 73,486.0 (10.4) 0.1988
Lactate (mmol/L) 7.0 ± 4.0 8.4 ± 4.8 0.3023
Average voltage (µV) 114.5 ± 54.2 91.5 ± 52.6 0.2178
Maximum voltage (µV) 217.4 ± 86.3 180.0 ± 103.1 0.1185
Dominant frequency (Hz) 2.4 ± 1.1 2.1 ± 1.3 0.1550
Country Clinical or EEG variable Alive and normal (N = 177) Alive with sequelae (N = 60) p value
Uganda + Malawi Age (years) 4.2 ± 2.2 3.7 ± 2.1 0.0723
Glucose (mg/dL) 7.0 ± 3.0 6.9 ± 4.7 0.1999
Parasitemia (parasites/µL) [geometric mean (coefficient of variation)] 29,312.6 (25.57) 38,422.1 (16.66) 0.4876
Lactate (mmol/L) 6.3 ± 4.0 6.1 ± 4.5 0.5321
Average voltage (µV) 101.9 ± 51.9 70.1 ± 38.4 < 0.0001
Maximum voltage (µV) 216.3 ± 81.8 194.6 ± 78.5 0.0943
Dominant frequency (Hz) 2.3 ± 1.0 2.0 ± 0.8 0.0524