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Fig. 1 | Malaria Journal

Fig. 1

From: Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts

Fig. 1

Natural compound screening for anti-malarial activity using 3D7 strain. a Plasmodium falciparum 3D7 strain-infected human RBCs were incubated with 10 µM test compounds (96 different compounds) for 96 h (see “Methods”). Five compounds showed almost 100% growth inhibitory effects. b The four selected compounds (berberine chloride, coptisine chloride, palmatine chloride, and dehydrocorydaline nitrate) were investigated for concentration-dependent growth inhibition effects. Six concentrations of each compound were incubated with parasites for 96 h. Concentration-dependent anti-malarial effects were observed and IC50 values were calculated (see Table 1)

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