Intermittent screening and treatment with artemether–lumefantrine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for malaria in pregnancy: a facility-based, open-label, non-inferiority trial in Nigeria

Table 4 Factors associated with low birth weight of babies delivered by study women (ATP analysis)

	Unadjusted RR	(95% CI)	p-value^a	Adjusted RR^b	(95% CI)	p-value
Treatment group
ISTp-AL	0.84	0.33–2.12	0.712	0.84	0.33–2.17	0.72
IPTp-SP	1			1
Age category
≤ 25	1			1
26–30	1.17	0.37–3.77	0.787	1.43	0.44–4.59	0.548
≥ 31	1.08	0.30–3.86	0.911	2.22	0.58–8.42	0.242
Baseline parasitaemia
Yes	1.46	0.35–5.99	0.603	1.62	0.39–6.63	0.505
No	1
Baseline mild anaemia
Yes	1.32	0.52–3.37	0.558	1.41	0.53–3.70	0.489
No	1
Gravidity
Primigravidae	3.18	0.73–13.81	0.123	4.54	0.94–21.84	0.059
Secundigravidae	1.31	0.23–7.65	0.761	1.44	0.24–8.69	0.694
Multigravidae	1

CI confidence interval
^ap ≤ 0.05 means observed differences between comparison groups is statistically significant or not significant if p > 0.05
^bRisk ratios were modelled using binomial regression. Treatment group, age category, baseline parasitaemia and mild anaemia, and gravidity were included in the final model

ISSN: 1475-2875