Fig. 1From: Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolatesStrategy for generation of constructs for parasite transfection. a PCR amplification of k13 gene with F446I mutation. b Insertion of PfK13F446I mut into the vector to generate the pARL-K13F446I recombinant plasmid. c Integration of PfK13F446I mut into the target locus of the parasite chromosome. d Integration of PfK13C580Y mut into the target locus of the parasite chromosomeBack to article page