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Table 1 The survival rates of transgenic parasite lines with either F446I or C580Y mutation and their parental strains (mean ± SD)

From: Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolates

Strains/lines RSA0–3 h at DHA 700 nM (%) RSA0–3 h at DHA 20 nM (%)
3D7wt 0 3.15 ± 0.13
3D7C580Ymut 0.91 ± 0.11 33.08 ± 1.20
3D7F446Imut 0.73 ± 0.10 26.0 ± 1.48
Fcc1/HNwt 0 2.86 ± 0.44
Fcc1/HNC580Ymut 0.63 ± 0.07 17.5 ± 0.80
Fcc1/HNF446Imut 0.53 ± 0.06 13.5 ± 0.41
F08-27 8.27 ± 0.63 65.8 ± 4.06
  1. Each assay was repeated for three times independently, with each group setting three technical repetitions