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Table 6 Performance of LM, RDT, LAMP and nPCR for diagnosing placental malaria in peripheral blood samples

From: Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening malaria in peripheral and placental blood samples from pregnant women in Colombia

Peripheral blood (N = 256)a

Value (95% CI)

Sensitivity

Specificity

Kappa

LM

0.0 (ND)

0.0 (ND)

0.0 (ND)

RDT

0.0 (ND)

0.0 (ND)

0.0 (ND)

LAMP

55.6% (26.7–81.0)

100% (98.8–100.0)

0.7 (0.4–1.0)

nPCR

55.6% (26.7–81.0)

100% (98.8–100.0)

0.7 (0.4–1.0)

  1. LM light microscopy, RDT rapid diagnostic test, LAMP loop-mediated isothermal amplification, nPCR nested polymerase chain reaction, CI confidence interval, N sample size, ND non-determined
  2. aPeripheral blood obtained at delivery from pregnant women who also provided placental blood. nPCR in placental blood was used as the reference test