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Table 3 Parasite clearance within 72 h based blood smears collected after every 8 h

From: High efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania

Item

Muheza—AL

Ujiji—AL

Muheza—DP

Ujiji—DP

Clearance rate constant (IQR) (/h)

0.23

0.25

0.22

0.28

(0.20, 0.28)

(0.21, 0.31)

(0.19, 0.27)

(0.23, 0.37)

Slope half-life (h)

2.96

2.75

3.09

2.51

(2.52, 3.52)

(2.22, 3.27)

(2.58, 3.64)

(1.85, 3.05)

P50 (h)a

11.22

8.54

6.81

6.08

(6.89, 14.00)

(5.37, 12.11)

(4.35, 10.60)

(3.77, 10.19)

P95 (h)b

20.34

17.49

17.4

14.76

(17.08, 23.43)

(14.30, 21.06)

(13.47, 20.43)

(12.36, 17.75)

  1. aEstimated time in hours for parasitaemia to decline by 50% of the initial values
  2. bEstimated time in hours for parasitaemia to decline by 95% of the initial values