Fig. 2

Expression of T-cell activation markers CD25/CD69 on T cells in PBMCs from the study cohort. a Representative flow cytometry gating strategy for phenotyping activation markers on CD4+ and CD8+ T cells ex vivo; the expression of the activation markers b CD25−CD69+ on T cells was analysed in healthy controls (n = 17), asymptomatic P. falciparum-infected children (n = 18), and symptomatic P. falciparum-infected children (n = 21). The data are presented as box plots with inter-quartile ranges. The 10th and 90th percentiles are presented as whiskers. Medians are indicated by the horizontal lines across the boxes. Kruskal–Wallis test was used for comparisons, followed by Dunn’s test where necessary