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Table 3 Frequency of the mutation and repetition AAG in the promoter region of the pvcrt-o gene in CQRPv and CQ susceptible P. vivax

From: Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon

 

Susceptible (%)

Resistant in D0 (%)

p

Resistant in DR (%)

p

Deletion 19 pb

 Yes

11 (47.6)

3 (23.1)

0.152

6 (55.5)

0.690

 No

12 (52.4)

10 (76.9)

 

5 (44.5)

 

Deletion 19 pb (4AAG)

 Yes

11 (47.6)

3 (23.1)

0.152

6 (55.5)

0.690

 No

12 (52.4)

10 (76.9)

 

5 (44.5)

 

Wild type (4AAG)

 Yes

2 (11.1)

1 (10.0)

0.927

1 (12.5)

0.919

 No

21 (88.9)

11 (90.0)

 

10 (87.5)

 

Wild type (5AAG)

 Yes

8 (33.3)

8 (60.0)

0.172

3 (25.0)

0.671

 No

15 (66.7)

5 (40.0)

 

8 (75.0)