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Table 2 Pharmacokinetic parameters of mefloquine in the presence of artesunate

From: Pharmacokinetics of mefloquine administered with artesunate in patients with uncomplicated falciparum malaria from the Brazilian Amazon basin

Parameter Value
Cmax (µg/ml) 3.1 (1.5–3.8)
AUC0−t (µg/ml h) 480 (330–60)
AUC0−∞ (µg/ml h) 484 (363–777)
Cl/f (liters/kg/h) 0.04 (0026–0058)
V/f (liters/kg) 13.2 (6–19)
t1/2 (days) 10.1 (7–16)
  1. Results are expressed as median and range