Table 2 Pharmacokinetic parameters of mefloquine in the presence of artesunate
Parameter | Value |
|---|---|
Cmax (µg/ml) | 3.1 (1.5–3.8) |
AUC0−t (µg/ml h) | 480 (330–60) |
AUC0−∞ (µg/ml h) | 484 (363–777) |
Cl/f (liters/kg/h) | 0.04 (0026–0058) |
V/f (liters/kg) | 13.2 (6–19) |
t1/2 (days) | 10.1 (7–16) |