Diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium knowlesi in Malaysia

Table 2 McDonald–Kreitman tests on TRAP of Plasmodium knowlesi and its domains with Plasmodium vivax and Plasmodium coatneyi orthologs as outgroup species

TRAP	Polymorphic changes within P. knowlesi		Fixed differences between species				Neutrality index
	Syn	NonSyn	Pk vs Pv		Pk vs Pco		Pk vs Pv	Pk vs Pco
	Syn	NonSyn	Syn	NonSyn	Syn	NonSyn	Pk vs Pv	Pk vs Pco
Full-length	21	53	144	174	84	126	2.10*	1.68^$
von Willebrand factor domain	4	16	47	50	24	38	3.76*	2.52
TSP domain	1	5	14	12	6	3	5.83	1.00
Proline/asparagine region	13	23	47	99	32	74	0.84	0.86

ISSN: 1475-2875