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Table 3 In-vitro drug sensitivity profile of the GAP MCB parasites

From: A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial

Drug

Control

Sample

3D7

W2

GAP MCB

Chloroquine

S

R

S

Dihydroartemisinina

S

S

S

Piperaquine

S

S

S

Lumefantrine

S

S

S

Amodiaquine

S

S

S

Atovaquonea

S

S

S

Pyronaridinea

S

S

S

Mefloquine

R

S

R

Quinine

S

R

S

  1. S drug sensitive, R drug resistant
  2. aInsufficient in vivo data to validate in vitro results; no established threshold values
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Malaria Journal

ISSN: 1475-2875

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