Table 1 Characteristics of study participants
Region | Malaria prevalencea, % | Woreda | Age in years, median (IQR) | Female sex, Â % (n/N) | Phenotypic G6PD deficiency, proportion deficient (n/N) | SNP frequency among G6PD normal individuals, proportion deficient (n/N) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
A376G | G202A | |||||||||||
Male | Female | Male hemizygotes | Female heterozygotes | Female homozygotes | Male hemizygotes | Female heterozygotes | Female homozygotes | |||||
Gambela | 18.4 | Abobo | 13 (8–25) | 46.5 (92/198) | 7.5 (8/106) | 5.4 (5/92) | 0 (0/5) | 37.5 (3/8) | 0 (0/8) | 0 (0/5) | 11.1 (1/9) | 0 (0/9) |
Lare | 14 (9–30) | 46.0 (91/198) | 1.9 (2/107) | 1.1 (1/91) | 8.3 (1/12) | 0 (0/8) | 12.5 (1/8) | 0 (/12) | 0 (0/8) | 0 (0/8) | ||
Benishangul Gumuz | 10.4 | Meng | 11 (6–30) | 46.3 (93/201) | 1.9 (2/108) | 0 (0/93) | 18.2 (2/11) | 33.3 (2/6) | 16.7 (1/6) | 0 (0/11) | 17.7 (1/6) | 0 (0/6) |
Mao-Komo | 16 (10–35) | 42.4 (84/198) | 0 (0/114) | 0 (0/84) | 0 (0/11) | 40.0 (4/10) | 0 (0/10) | 0 (0/11) | 0 (0/10) | 0 (0/10) | ||
Amhara | 1.1 | Bahir Dar Zuria | 13 (12–14) | 46.9 (52/111) | 0 (0/59) | 0 (0/52) | 0 (0/8) | 11.1 (1/9) | 22.2 (2/9) | 0 (0/7) | 0 (0/9) | 0 (0/9) |
Achefer | 13 (12–14) | 52.9 (55/104) | 0 (0/49) | 0 (0/55) | 0 (0/6) | 16.7 (2/12) | 0 (0/12) | 0 (0/6) | 0 (0/12) | 0 (0/12) | ||
Jawi | 13 (12–14) | 50.5 (55/109) | 0 (0/54) | 0 (0/55) | 0 (0/10) | 12.5 (1/8) | 12.5 (1/8) | 0 (0/10) | 0 (0/8) | 0 (0/8) | ||
Oromia | 0.7 | Adama | 13 (8.5–31.5) | 23.8 (20/84) | 0 (0/64) | 0 (0/20) | 17.9 (5/28) | 0 (0/9) | 11.1 (1/9) | 14.3 (4/28) | 0 (0/9) | 0 (0/9) |
Goma | 25 (10–40) | 50.8 (203/400) | 0.5 (1/197) | 1.5 (3/203) | 5.0 (1/20) | 29.4 (5/17) | 5.9 (1/17) | 0 (0/20) | 5.9 (1/17) | 0 (0/17) | ||
Total | 0.1 | – | 14 (10–30) | 46.3 (745/1609) | 1.5 (13/864) | 1.2 (9/745) | 8.1 (9/111) | 20.7 (18/87) | 8.1 (7/87) | 3.6 (4/111) | 3.4 (3/88) | 0 (0/88) |