Skip to main content

Advertisement

Table 1 Characteristics of study participants

From: Low and heterogeneous prevalence of glucose-6-phosphate dehydrogenase deficiency in different settings in Ethiopia using phenotyping and genotyping approaches

Region Malaria prevalencea, % Woreda Age in years, median (IQR) Female sex,  % (n/N) Phenotypic G6PD deficiency, proportion deficient (n/N) SNP frequency among G6PD normal individuals, proportion deficient (n/N)
A376G G202A
Male Female Male hemizygotes Female heterozygotes Female homozygotes Male hemizygotes Female heterozygotes Female homozygotes
Gambela 18.4 Abobo 13 (8–25) 46.5 (92/198) 7.5 (8/106) 5.4 (5/92) 0 (0/5) 37.5 (3/8) 0 (0/8) 0 (0/5) 11.1 (1/9) 0 (0/9)
Lare 14 (9–30) 46.0 (91/198) 1.9 (2/107) 1.1 (1/91) 8.3 (1/12) 0 (0/8) 12.5 (1/8) 0 (/12) 0 (0/8) 0 (0/8)
Benishangul Gumuz 10.4 Meng 11 (6–30) 46.3 (93/201) 1.9 (2/108) 0 (0/93) 18.2 (2/11) 33.3 (2/6) 16.7 (1/6) 0 (0/11) 17.7 (1/6) 0 (0/6)
Mao-Komo 16 (10–35) 42.4 (84/198) 0 (0/114) 0 (0/84) 0 (0/11) 40.0 (4/10) 0 (0/10) 0 (0/11) 0 (0/10) 0 (0/10)
Amhara 1.1 Bahir Dar Zuria 13 (12–14) 46.9 (52/111) 0 (0/59) 0 (0/52) 0 (0/8) 11.1 (1/9) 22.2 (2/9) 0 (0/7) 0 (0/9) 0 (0/9)
Achefer 13 (12–14) 52.9 (55/104) 0 (0/49) 0 (0/55) 0 (0/6) 16.7 (2/12) 0 (0/12) 0 (0/6) 0 (0/12) 0 (0/12)
Jawi 13 (12–14) 50.5 (55/109) 0 (0/54) 0 (0/55) 0 (0/10) 12.5 (1/8) 12.5 (1/8) 0 (0/10) 0 (0/8) 0 (0/8)
Oromia 0.7 Adama 13 (8.5–31.5) 23.8 (20/84) 0 (0/64) 0 (0/20) 17.9 (5/28) 0 (0/9) 11.1 (1/9) 14.3 (4/28) 0 (0/9) 0 (0/9)
Goma 25 (10–40) 50.8 (203/400) 0.5 (1/197) 1.5 (3/203) 5.0 (1/20) 29.4 (5/17) 5.9 (1/17) 0 (0/20) 5.9 (1/17) 0 (0/17)
Total 0.1 14 (10–30) 46.3 (745/1609) 1.5 (13/864) 1.2 (9/745) 8.1 (9/111) 20.7 (18/87) 8.1 (7/87) 3.6 (4/111) 3.4 (3/88) 0 (0/88)
  1. SNP single nucleotide polymorphism
  2. aData was obtained from the 2015 National Malaria Indicator Survey (MIS 2015). Results indicate RDT positivity among all age groups screened during the study period. SNP data for A376G and G202A (at the right end of the table) is given for the phenotypically normal individuals only. IQR, 25th–75th percentile