Table 1 Baseline clinical and parasitological characteristics of enrolled patients in the 6 sites, Madagascar, 2012–2016, ASAQ
Epidemiological strata | Eastern Madagascar (equatorial stratum) | Western Madagascar (tropical stratum) | Fringe highlands of Madagascar (fringe highlands stratum) | |||
|---|---|---|---|---|---|---|
Site | Matanga | Tsaratanana | Ankazomborona | Antanimbary | Ampasipotsy | Anjoma Ramartina |
District | Vangaindrano | Ifanadiana | Marovoay | Maevatanana | Tsiroanomandidy | Mandoto |
Year | 2012 | 2016 | 2013 | 2016 | 2012 | 2013 |
n | 64 | 67 | 63 | 50 | 44 | 60 |
Age years, median (range) | 2.17 (1–34) | 6 (1–14) | 9 (1–54) | 11 (1–56) | 174 (2–56) | 10 (2–45) |
Gender male, n (%) | 35 (54,69) | 24 (35,82) | 29 (46,03) | 28 (35,82) | 27 (61,36) | 30 (50) |
Axillary T°, mean (SD) | 38.05 (1.38) | 38.42 (1.02) | 37.83 (1.46) | 38.38 (1.29) | 37.91 (1.14) | 37.96 (1.31) |
Parasite density/µl | 20,803.67 | 28,089.02 | 21,517.67 | 22,301.17 | 7315.71 | 10,704.84 |
Parasite density (geometric mean, range) | 1005–199,800 | 1561–185,103 | 1448–198,400 | 1168–151,844 | 1056–85,000 | 1009–149,747 |
Age group, n (%) | ||||||
Under 5 | 55 (85.94) | 25 (37.35) | 13 (20.63) | 7 (14) | 3 (6.82) | 13 (21.70) |
5–15 | 8 (12.5) | 42 (62.65) | 35 (55.56) | 28 (56) | 19 (43.18) | 30 (50) |
Adult | 1 (1.56) | 0 (0) | 15 (23.81) | 15 (30) | 22 (50) | 17 (28.30) |
Haemoglobin g/dl (mean, SD) | ND | 10.24 (1.90) | 11.25 (1.90) | 10.76 (1.92) | ND | 10.43 (2.21) |
Hb < 10 g/dl, n (%) | ND | 29 (43.3) | 14 (22.23) | 16 (32) | ND | 21 (35) |