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Table 2 A summary of results of the different diagnostic parameters compared to CNM-PCR

From: Study of the diagnostic accuracy of microbiological techniques in the diagnosis of malaria in the immigrant population in Madrid

Global, (n)

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

PLR (95% CI)

NLR (95% CI)

Efficiency (95% CI)

Kappa score (95% CI)

RDT (n = 178)

88.88 (76.50–95.16)

84.21 (77.06–89.43)

95.24 (87.61–100)

97.01 (93.76–100)

60 (15.12–238.14)

0.09 (0.04–0.24)

96.5 (93.63–99.56)

0.65 (0.53–0.77)

Thick blood slide, (n = 234)

88.46 (79.50–93.80)

100 (97.59–100)

100 (99.28–100)

94.55 (90.78–98.31)

0.12 (0.06–0.21)

96.59 (93.86–99.32)

0.91 (0.85–0.96)

C-PCR, (n = 228)

96.00 (88.88–98.63)

97.38 (93.47–98.97)

93.59 (87.51–99.67)

98.04 (95.52–100)

29.78 (12.56–70.61)

0.04 (0.01–0.12)

96.97 (94.33–99.61)

0.93 (0.88–0.98)

  1. PPV positive predictive value, NPV negative predictive value, PLR positive likelihood ratio, NLR negative likelihood ratio