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Table 3 Correlation between total IgG and subclass (IgG1, IgG2, IgG3 and IgG4) response levels to Pf-ESAs stratified by asymptomatic or symptomatic carriers

From: IgG subclass responses to excreted-secreted antigens of Plasmodium falciparum in a low-transmission malaria area of the Peruvian Amazon

  IgG1 IgG2 IgG3 IgG4
All individuals
 IgG 0.53 (***) 0.45 (**) 0.52 (***) − 0.14 (ns)
 IgG1   0.23 (ns) 0.47 (**) 0.14 (ns)
 IgG2    0.68 (***) 0.24 (ns)
 IgG3     0.38 (**)
Asymptomatic
 IgG 0.56 (**) 0.32 (ns) 0.57 (**) − 0.09 (ns)
 IgG1   0.07 (ns) 0.63 (***) 0.32 (ns)
 IgG2    0.40 (*) 0.10 (ns)
 IgG3     0.29 (ns)
Symptomatic
 IgG 0.52 (*) 0.77 (***) 0.68 (***) 0.33 (ns)
 IgG1   0.34 (ns) 0.36 (ns) 0.22 (ns)
 IgG2    0.90 (***) 0.57 (**)
 IgG3     0.50 (*)
  1. Correlation coefficients were determined by Spearman’s method
  2. ns non-significant
  3. * P < 0.05; ** P < 0.01; *** P < 0.001