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Table 2 Clinical and laboratory features of two groups

From: A pilot randomized controlled trial to compare the effectiveness of two 14-day primaquine regimens for the radical cure of vivax malaria in South India

 

PQ high dose (N = 25) n (%) or Mean ± SD or Median (IQR)

PQ low dose (N = 25) n (%) or Mean ± SD or Median (IQR)

p-value

Fever

25 (100)

25 (100)

 

Splenomegaly

3 (12)

2 (8)

0.63

Hepatomegaly

2 (8)

2 (8)

1.00

Haemoglobin, gm/dl

13.2 ± 1.7

13.5 ± 1.7

0.45

Urea, mg/dl

33.3 ± 19.9

31.7 ± 13.4

0.43

Creatinine, mg/dl

1.2 ± 0.4

1.1 ± 0.4

0.36

Total bilirubin, mg/dl

1.4 (1.3, 1.9)

1.5 (0.95, 3.0)

0.36

Direct bilirubin, mg/dl

0.6 (0.3, 0.8)

0.6 (0.3, 1.4)

0.12

Aspartate amino transferase, IU/l

39.5 (35.5, 54.0)

30.0 (27.0, 41.0)

0.38

Alanine amino transferase, IU/l

40.5 (29.0, 67.0)

34.0 (24.0, 44.0)

0.67

Alkaline phosphatase, IU/l

87.0 (62.5, 118.5)

82.0 (57.0, 110.0)

0.34

PQ concentration (µg/ml) (N = 30)

0.576 (0.186, 0.782)

0.184 (0.131, 0.282)

0.193

Carboxy PQ concentration (µg/ml) (N = 30)

2.401 (1.535, 4.119)

2.809 (0.817, 6.658)

0.945