PQ high dose (N = 25) n (%) or Mean ± SD or Median (IQR) | PQ low dose (N = 25) n (%) or Mean ± SD or Median (IQR) | p-value | |
---|---|---|---|
Fever | 25 (100) | 25 (100) | |
Splenomegaly | 3 (12) | 2 (8) | 0.63 |
Hepatomegaly | 2 (8) | 2 (8) | 1.00 |
Haemoglobin, gm/dl | 13.2 ± 1.7 | 13.5 ± 1.7 | 0.45 |
Urea, mg/dl | 33.3 ± 19.9 | 31.7 ± 13.4 | 0.43 |
Creatinine, mg/dl | 1.2 ± 0.4 | 1.1 ± 0.4 | 0.36 |
Total bilirubin, mg/dl | 1.4 (1.3, 1.9) | 1.5 (0.95, 3.0) | 0.36 |
Direct bilirubin, mg/dl | 0.6 (0.3, 0.8) | 0.6 (0.3, 1.4) | 0.12 |
Aspartate amino transferase, IU/l | 39.5 (35.5, 54.0) | 30.0 (27.0, 41.0) | 0.38 |
Alanine amino transferase, IU/l | 40.5 (29.0, 67.0) | 34.0 (24.0, 44.0) | 0.67 |
Alkaline phosphatase, IU/l | 87.0 (62.5, 118.5) | 82.0 (57.0, 110.0) | 0.34 |
PQ concentration (µg/ml) (N = 30) | 0.576 (0.186, 0.782) | 0.184 (0.131, 0.282) | 0.193 |
Carboxy PQ concentration (µg/ml) (N = 30) | 2.401 (1.535, 4.119) | 2.809 (0.817, 6.658) | 0.945 |