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Table 1 Properties of the study population as reported/measured in individual cases

From: Proteomic profiling of the plasma of Gambian children with cerebral malaria

 

Survived (N = 26)

Died (N = 26)

P value

Sex (male/female)

14/15

15/9

0.33

Age (median, IQR) months

60 (35–95)

48 (24–83)

0.32

Hb (mean, SD) g/dl

7.27 (1.93)

8.03 (2.15)

0.07

Respiratory distressa (%)

24.1

66.6

0.002

Convulsions on admission (%)

75

69.2

0.77

Deep coma (%)a

31

54

0.08

Transfused (%)

37.9

45.8

0.56

P. falciparum (geo mean, 95% CI) parasites/µl

35,341 (18,759–66,581)

55,792 (28,797–108,095)

0.051

Protein biomarkers

Circulating 20S proteasomes (ng/ml)

39.4 (19.6–49.4)

22.7 (16–34.5)

0.20

PSMB9 (ng/ml)

177 (129–267)

209 (161–271)

0.49

  1. aDeep coma was defined as a Blantyre Coma score of 0 or 1. Respiratory distress was defined as the presence of deep breathing, irregular breathing, or chest in-drawing