Fig. 1

Overview of the global burden of malaria in children under five. There were an estimated 216 million cases of malaria infection in 2016. The majority of malaria cases and fatalities occur in sub-Saharan Africa. An estimated ≤ 1% of all malaria infections present with or progress to severe disease, which is associated with an increased risk of morbidity and mortality. Current barriers to improved management and outcome for paediatric febrile illnesses include the lack of simple and rapid tools to enhance triage and referral of severe malaria and other life-threatening infections [7], Licence: CC BY-NC-SA 3.0 IGO