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Table 5 Most frequent adverse events after 28 days of treatment

From: Efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated malaria in Papua New Guinea

Adverse events AL DHA-PPQ P-value*
(N = 157) (N = 187)
Patients with at least one adverse event 87 (55.4) 112 (59.9) 0.443
Abdominal pain 17 (10.8) 10 (5.3) 0.071
Chills 12 (7.6) 15 (8.0) 1.0
Cough 60 (38.2) 71 (38.0) 1.0
Diarrhoea 11 (7.0) 8 (4.3) 0.345
Headache 16 (10.2) 35 (18.7) 0.033
Vomit 4 (2.5) 6 (3.2) 0.760
Ear pain 3 (1.9) 2 (1.1) 0.663
Running nose 19 (12.1) 41 (21.9) 0.022
Skin rash 1 (0.6) 2 (1.1) 1.0
Shortness of breath 1 (0.6) 2 (1.1) 1.0
Fits 1 (0.6) 2 (1.1) 1.0
Stiff neck 1 (0.6) 1 (0.5) 1.0
  1. Values are presented n (%)
  2. * Fisher’s exact test