A randomized trial of dihydroartemisinin–piperaquine versus artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali

Table 3 Clinical and parasitological response at 42-day before and after PCR correction

Treatment arm outcome	AL n (%)	DHA–PQ n (%)	p-value
Before PCR correction
LCF	9 (5.8)	4 (2.6)	0.15
LPF	32 (20.8)	5 (3.2)	< 0.0001
ACPR^a	113 (73.4)	146 (94.2)	< 0.0001
Total	154 (100)	155 (100)
After PCR correction
LCF	0 (0.00)	1 (0.7)	1
LPF	4 (2.6)	0 (0.00)	0.06
ACPRc	150 (97.4)	154 (99.3)	0.2
Total	154 (100)	155 (100)

ACPRc was not statistically different between DHA–PQ versus AL (p = 0.2)
^aNon-PCR corrected Adequate Clinical and Parasitological Response was statistically different between DHA–PQ versus AL

ISSN: 1475-2875