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Table 3 Clinical and parasitological response at 42-day before and after PCR correction

From: A randomized trial of dihydroartemisinin–piperaquine versus artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali

Treatment arm outcome AL
n (%)
DHA–PQ
n (%)
p-value
Before PCR correction
 LCF 9 (5.8) 4 (2.6) 0.15
 LPF 32 (20.8) 5 (3.2) < 0.0001
 ACPRa 113 (73.4) 146 (94.2) < 0.0001
 Total 154 (100) 155 (100)  
After PCR correction
 LCF 0 (0.00) 1 (0.7) 1
 LPF 4 (2.6) 0 (0.00) 0.06
 ACPRc 150 (97.4) 154 (99.3) 0.2
 Total 154 (100) 155 (100)  
  1. ACPRc was not statistically different between DHA–PQ versus AL (p = 0.2)
  2. aNon-PCR corrected Adequate Clinical and Parasitological Response was statistically different between DHA–PQ versus AL