Skip to main content

Table 1 Prevalence of RDT negative samples along with gene deletions at pfhrp2 and pfhrp3 in different region and seasons of the year

From: High proportions of pfhrp2 gene deletion and performance of HRP2-based rapid diagnostic test in Plasmodium falciparum field isolates of Odisha

Parameters

Samples screened

Positive for P. falciparuma

HRP2 negative

Gene deletion in Pfhrp2 and hrp3 in HRP2 negative samples

PfHRP2

PfHRP3

PfHRP2 and PfHRP3

Positive

Negative

Positive

Negative

Positive

Negative

Geophysical region

 Northern plateau

289

97

16 (16.5)

07 (12.1)

09 (15.5)

10 (17.2)

06 (10.3)

04

03 (5.2)

 Coastal tract

243

76

10 (13.15)

04 (6.9)

06 (10.3)

07 (12.1)

03 (5.2)

03 (5.2)

02 (3.4)

 Central table land

409

163

22 (13.5)

06 (10.3)

16 (27.6)

08 (13.8)

14 (24.1)

03 (5.2)

11 (19)

 Eastern ghat

117

48

10 (20.83)

03 (5.2)

07 (12.1)

09 (15.5)

01 (1.7)

03 (5.2)

01 (1.72)

Season

 Summer

79

17

09 (52.94)

02 (3.4)

07 (12.1)

06 (10.3)

03 (5.2)

02 (3.4)

03 (5.2)

 Rainy

767

345

45 (13.04)

16 (27.6)

29 (50)

25 (43.1)

20 (34.5)

09 (15.5)

13 (22.4)

 Winter

212

22

04 (18.18)

02 (3.4)

02 (3.4)

03 (5.2)

01 (1.7)

02 (3.4)

01 (1.72)

Gender

 Male

672

299

44 (14.71)

18 (31)

26 (44.8)

29 (50)

15 (25.9)

13 (22.4)

10 (17.2)

 Female

386

85

14 (16.47)

02 (3.4)

12 (20.7)

05 (8.6)

09 (15.5)

0

07 (12.1)

Multiplicity of infections

 SGI

–

ND

39 (67.2)

12 (20.7)

27 (46.6)

24 (41.4)

15 (25.9)

10 (17.2)

13 (22.4)

 MGI

–

ND

19 (32.8)

08 (13.8)

11 (19)

10 (17.2)

09 (15.5)

03 (5.2)

04 (6.9)

 Total

1058

384

58 (15.1)

20 (34.5)

38 (65.5)

34 (58.6)

24 (41.4)

13 (22.4)

17 (29.31)

  1. Value within the parentheses for HRP2 negative are percentage value derived from total number of P. falciparum positive samples in each region, season or gender, whereas for gene deletion percentage values were calculated from total number of 58 samples negative by RDT
  2. ND Not determined for RDT positive samples, only RDT negative samples were screened for msp1 and msp2 typing for quality check of DNA and multiple genotype infections
  3. aMono infected Plasmodium falciparum cases by microscopy