Skip to main content

Table 1 Prevalence of RDT negative samples along with gene deletions at pfhrp2 and pfhrp3 in different region and seasons of the year

From: High proportions of pfhrp2 gene deletion and performance of HRP2-based rapid diagnostic test in Plasmodium falciparum field isolates of Odisha

Parameters Samples screened Positive for P. falciparuma HRP2 negative Gene deletion in Pfhrp2 and hrp3 in HRP2 negative samples
PfHRP2 PfHRP3 PfHRP2 and PfHRP3
Positive Negative Positive Negative Positive Negative
Geophysical region
 Northern plateau 289 97 16 (16.5) 07 (12.1) 09 (15.5) 10 (17.2) 06 (10.3) 04 03 (5.2)
 Coastal tract 243 76 10 (13.15) 04 (6.9) 06 (10.3) 07 (12.1) 03 (5.2) 03 (5.2) 02 (3.4)
 Central table land 409 163 22 (13.5) 06 (10.3) 16 (27.6) 08 (13.8) 14 (24.1) 03 (5.2) 11 (19)
 Eastern ghat 117 48 10 (20.83) 03 (5.2) 07 (12.1) 09 (15.5) 01 (1.7) 03 (5.2) 01 (1.72)
Season
 Summer 79 17 09 (52.94) 02 (3.4) 07 (12.1) 06 (10.3) 03 (5.2) 02 (3.4) 03 (5.2)
 Rainy 767 345 45 (13.04) 16 (27.6) 29 (50) 25 (43.1) 20 (34.5) 09 (15.5) 13 (22.4)
 Winter 212 22 04 (18.18) 02 (3.4) 02 (3.4) 03 (5.2) 01 (1.7) 02 (3.4) 01 (1.72)
Gender
 Male 672 299 44 (14.71) 18 (31) 26 (44.8) 29 (50) 15 (25.9) 13 (22.4) 10 (17.2)
 Female 386 85 14 (16.47) 02 (3.4) 12 (20.7) 05 (8.6) 09 (15.5) 0 07 (12.1)
Multiplicity of infections
 SGI ND 39 (67.2) 12 (20.7) 27 (46.6) 24 (41.4) 15 (25.9) 10 (17.2) 13 (22.4)
 MGI ND 19 (32.8) 08 (13.8) 11 (19) 10 (17.2) 09 (15.5) 03 (5.2) 04 (6.9)
 Total 1058 384 58 (15.1) 20 (34.5) 38 (65.5) 34 (58.6) 24 (41.4) 13 (22.4) 17 (29.31)
  1. Value within the parentheses for HRP2 negative are percentage value derived from total number of P. falciparum positive samples in each region, season or gender, whereas for gene deletion percentage values were calculated from total number of 58 samples negative by RDT
  2. ND Not determined for RDT positive samples, only RDT negative samples were screened for msp1 and msp2 typing for quality check of DNA and multiple genotype infections
  3. aMono infected Plasmodium falciparum cases by microscopy