Test | Sensitivity [95% CI] | Specificity [95% CI] |
---|
PURE–LAMP Pan | 96.96% [89.47–99.63] | 100% |
PURE–LAMP Pf | 97.82% [88.47–99.94] | 100% |
Microscopy | 93.93% [85.20–98.32] | 100% |
RDT | T1: 100% T2: 68.18% [55.56–79.11] | T1: 92.95% [84.32–97.67] T2: 100% |
- PURE–LAMP procedure for ultra rapid extraction-loop-mediated isothermal amplification, RDT rapid diagnostic test, PCR polymerase chain reaction, CI confidence interval, Pan Plasmodium genus, Pf P. falciparum, T1 band of the rapid test containing the antibody for detection of a Plasmodium falciparum-specific HRP2 antigen, T2 band containing the antibody for detection of a Plasmodium common aldolase antigen