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Fig. 6 | Malaria Journal

Fig. 6

From: A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

Fig. 6

An atg18 SNP does not alter IC50 values for common anti-malarial compounds in isogenic lines Dose response curves from a ART and two derivatives, b DHA, and c artesunate, which are used in Cambodia and elsewhere in Southeast Asia. Also shown are dose response curves for d chloroquine, e mefloquine, and f piperaquine, long-lasting partner drugs which have been recently used in Cambodia and elsewhere in Southeast Asia. Parent displayed in blue, mutant in red. Drug structures are also shown

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