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Table 2 Number of DBS samples analysed and prevalence of G6PD*A (A376G) mutants by region

From: Glucose-6-phosphate dehydrogenase (G6PD) deficiency in Ethiopia: absence of common African and Mediterranean allelic variants in a nationwide study

Region No. of samples extracted No. of samples amplified No. of samples merged for analysis No. G6PD*A (A376G) mutants observed Weighted prevalence (%) of G6PD*A (A376G) mutation (95% CI)
Afar and Somali 152 128 (84.2%) 118 (77.6%) 7 7.7 (0.5–14.9)
Amhara 302 262 (86.8%) 229 (75.8%) 15 7.5 (3.0–12.0)
Benishangul-Gumuz and Gambella 118 117 (99.2%) 109 (92.4%) 8 5.3 (0.7–10.0)
Dire Dawa and Harari 11 11 (100%) 10 (90.9%) 0 0
Oromia 640 633 (98.9%) 576 (90.0%) 58 8.0 (5.0–10.9)
Southern Nations, Nationalities, and Peoples’ 277 256 (92.4%) 240 (86.6%) 28 12.2 (5.7–18.7)
Tigray 141 141 (100%) 132 (93.6%) 14 12.0 (4.4–19.5)
Total 1641 1548 1414 130 8.9 (6.7–11.2)
  1. No G6PD*A− (G202A) and Mediterranean (C563T) variants were observed