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Table 1 The estimates of DNA sequence polymorphism and tests of neutrality at pfama1 among PKH P. falciparum isolates along with global samples

From: Population genetic structure of domain I of apical membrane antigen-1 in Plasmodium falciparum isolates from Hazara division of Pakistan

Isolates

Segregating sites (S)

Singleton variable sites

Parsimony informative sites

Total no. of mutations

K

H

Hd ± SD

π

Tajima’s D

Fu and Li’s D

Fu and Li’s F

Ghana

35

7

28

39

12.04211

16

0.979 ± 0.021

0.02888

0.37976

(P > 0.10)

0.37631

(P > 0.10)

0.43962

(P > 0.10)

PNG

28

2

26

31

11.495

13

0.963 ± 0.023

0.02757

1.23920

(P > 0.10)

1.29980

(P > 0.05)

1.49238

(P > 0.05)

India

33

7

26

37

11.053

19

0.9947 ± 0.00032

0.02651

0.23721

(P > 0.10)

− 0.00337 (P > 0.10)

0.07966 (P > 0.10)

Myanmar

25

7

18

26

6.326

9

0.653 ± 0.122

0.01517

− 0.53086

(P > 0.10)

− 0.06044

(P > 0.10)

− 0.23238

(P > 0.10)

PKH

35

2

12

14

5.395

5

0.616 ± 0.106

0.01294

1.34376

(P > 0.10)

0.77839

(P > 0.10)

1.09423

(P > 0.10)

Philippines

29

4

25

30

11.053

9

0.911 ± 0.032

0.02651

1.20358

(P > 0.10)

0.72573

(P > 0.10)

1.01009 (P > 0.10)

Solomon

24

0

24

25

10.263

4

0.742 ± 0.056

0.02461

1.76659 (0.10 > P > 0.05)

1.62535

(0.10 > P < 0.02)

1.93964 (0.10 > P < 0.02)

Tanzania

35

6

29

39

11.979

16

0.963 ± 0.033

0.02873

0.35690

(P > 0.10)

0.52264

(P > 0.10)

0.55126

(P > 0.10)

Thailand

26

0

26

27

10.021

10

0.916 ± 0.040

0.02403

1.23278

(P > 0.10)

1.43415

(P < 0.05)

1.59960

(0.10 > P > 0.05)

Vanuatu

23

3

20

23

9.874

4

0.616 ± 0.067

0.02368

2.01117

(P < 0.05)

0.90227 (P > 0.10)

1.43009

(P > 0.10)

  1. PKH Pakistani Hazara, PNG Papua New Guinea