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Table 5 Prevalence and incidence of symptomatic P. falciparum in early MDA and deferred-MDA villages during tri-monthly follow-up

From: The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin–piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos

Variables

Village status

Baseline

Follow-up time

M0

M3

M6

M9

M12

Number of villagersa

Early MDA

883

889

877

879

899

Deferred-MDA

1036

1029

1071

1022

1022

Number of Pf clinical caseb

Early MDA

1

0

8

1

0

Deferred-MDA

2

2

26

8

0

Prevalence of Pf clinical case 95% CI

Early MDA

 

0.0 (0.0–0.4)

0.9 (0.4–1.7)

0.1 (0.0–0.6)

0

Deferred-MDA

 

0.2 (0.2–0.7)

2.4 (1.6–3.5)

0.8 (0.3–1.5)

0

p-value

0.192

0.008

0.035

 

PF exposure time (person-year)

Early MDA

N/A

222

219

220

220

Deferred-MDA

N/A

257

268

256

205

Incidence of clinical Pf infection 95% CI (per 1000 person-years)

Early MDA

N/A

0 (0–6.6)

36 (16–72)

4.6 (0.1–25.3)

0

Deferred-MDA

N/A

8 (0.9–28.1)

97 (63–142)

31 (13.5–61.6)

0

p-value

0.288

0.011

0.037

 
  1. aNumber of villagers who have RDT result
  2. bConfirmed by RDT