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Table 1 Epidemiological parameters of the subjects exposed to malaria in the gold mining region (Itaituba)

From: Genetic sequence characterization and naturally acquired immune response to Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2)

Characteristics Infected (93) Non-infected (97) p*
Gender, male (%) 80.6 62.4 0.001
Age, median years (range) 32 43 < 0.0001
Past malaria infections    
 ≥ 4 41.6 74.2 < 0.0001
 < 4 58.4 25.8  
Haemoglobin (g/dL) 14.0 14.3  
Anaemia (%) 24.7 9.3 0.008
Platelets (cells/mm3) 104,000 190,000  
Thrombocytopaenic (%) 79.6 19.6 < 0.0001
Cytokines (pg/mL)    
 INF-γ 2.04 0 0.0002
 IL-6 24.38 3.02 < 0.0001
 IL-10 81.95 0.22 < 0.0001
 IL-2 0 0 0.09
 IL-4 0 0 0.63
 TNF-α 3.09 0.86 0.03
  1. Anaemia was considered positive when haemoglobin levels were under 13 g/dL for men or under 12 g/dL for women
  2. Thrombocytopaenia was defined as a platelet count of less than 150 × 103 per µL
  3. * p-values were calculated from the Chi-squared test for qualitative variables or the Mann–Whitney test for non-parametric continuous variables